Bioscience, Biotechnology, and Biochemistry 2007-07-01

Oxidative dimer produced from a 2,3,4-trihydroxybenzoic ester.

Asuka Kodama, Hidetoshi Shibano, Jun Kawabata

文献索引：Biosci. Biotechnol. Biochem. 71(7) , 1731-4, (2007)

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摘要

The DPPH radical-scavenging abilities of the naturally occurring phenolic acid, 2,3,4-trihydroxybenzoic acid, and its methyl ester were evaluated. Both compounds in acetonitrile scavenged as many as four radicals compared to three or fewer radical consumption in acetone or ethanol. Only the ester showed relatively high ability in methanol. Oxidation with o-chloranil in acetonitrile resulted in methyl 2,3,4-trihydroxybenzoate giving a novel benzocoumarin-type dimer, its chemical structure being confirmed by spectroscopic evidence. The formation of this dimer might partly account for the higher radical-scavenging efficiency of the ester in acetonitrile or methanol.