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Tetrahedron

A synthesis of some pyridinylpyrimidines from ketenedithioacetals

RB Katz, MB Mitchell, PG Sammes, RJ Ife

文献索引:Katz, Ruth B.; Mitchell, Michael B.; Sammes, Peter G.; Ife, Robert J. Tetrahedron, 1989 , vol. 45, # 6 p. 1801 - 1814

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被引用次数: 6

摘要

Some studies are reported on the preparation of a new class of substituted 5-(2-pyridinyl) pyrimidines, starting with cyano (2-pyridinyl) ketenedithioacetal. This has been reacted with amidines under base-catalysed conditions, giving a variety of different products, the structures of which have been determined. Synthesis of two novel tricyclic systems,(29) and (30), have also been developed.