Synthesis of 8??substituted 5??deazaflavins

PAJ Link, HC Van Der Pias…

文献索引：Link, P. A. J.; Plas, H. C. van der; Mueller, F. Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 841 - 848

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被引用次数: 10

摘要

Abstract To obtain 5-deazaflavins exhibiting red-shifted light absorption spectra, a number of C (8) substituted 5-deazaisoalloxazines were synthesized. This was accomplished a) by the oxidative cyclization of 5, 5′-arylmethylenebis (6-methylaminouracil) derivatives and b) by the cyclization of N-methylanilinouracil derivatives with a one-carbon reagent. The latter method led to the formation of impure products. Condensation and oxidation reactions ...