Synthesis of benzimidazolyl-1, 3, 4-oxadiazol-2ylthio-N-phenyl (benzothiazolyl) acetamides as antibacterial, antifungal and antituberculosis agents

…, PK Patel, P Kumari, DP Rajani, KH Chikhalia

文献索引：Patel, Rahul V.; Patel, Paresh K.; Kumari, Premlata; Rajani, Dhanji P.; Chikhalia, Kishor H. European Journal of Medicinal Chemistry, 2012 , vol. 53, p. 41 - 51

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被引用次数: 77

摘要

To affiliate multiple bioactivities in a compact heteronuclei, two series of benzimidazole based 1, 3, 4-oxadiazoles were synthesized and assessed in vitro for their efficacy as antimicrobial agents against eight bacteria (Staphylococcus aureus, Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Salmonella typhi, Proteus vulgaris, Shigella flexneri), four fungi (Aspergillus niger, Aspergillus fumigatus, ...