Synthesis and SAR of novel imidazoquinoxaline-based Lck inhibitors: improvement of cell potency

P Chen, EJ Iwanowicz, D Norris, HH Gu, J Lin…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3153 - 3156

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被引用次数: 29

摘要

... Bioorganic & Medicinal Chemistry Letters. ... As outlined in Scheme 1, two general approaches were taken to prepare the key intermediate, the imidazo[1,5-a]quinoxalin- 4(5H)-one 4, using the chemistry developed in this lab. ...