The Journal of Organic Chemistry

The Synthesis of β-Diketones Containing Chlorodifluoromethyl and Perfluoroethyl Groups and Certain Related Reactions1

RA Moore, R Levine

文献索引：Moore,R.A.; Levine,R. Journal of Organic Chemistry, 1964 , vol. 29, p. 1439 - 1444

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被引用次数: 35

摘要

A series of p-diketones of the type RCOCH&OR', where R= CFzCl and C2F5, and R'= alkyl, aryl, and heterocyclic, has been prepared in high yields by the sodium methoxide-effected acylation8 of the appropriate ketones with methyl chlorodifluoroacetate and methyl pentafluoropropionate. While CFzClCOCHa (I) and CzF5COCH3 (VII) may be acylated under basic conditions with the very reactive esters methyl chlorodifluoroacetate and ...