Bioorganic & Medicinal Chemistry Letters 2005-02-01

Acyl sulfonamide anti-proliferatives. Part 2: activity of heterocyclic sulfonamide derivatives.

Mary M Mader, Chuan Shih, Eileen Considine, Alfonso De Dios, Cora Sue Grossman, Philip A Hipskind, Ho-Shen Lin, Karen L Lobb, Beatriz Lopez, José E Lopez, Luisa M Martin Cabrejas, Michael E Richett, Wesley T White, Yiu-Yin Cheung, Zhongping Huang, John E Reilly, Sean R Dinn

文献索引：Bioorg. Med. Chem. Lett. 15(3) , 617-20, (2005)

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摘要

The anti-proliferative activity of acylated heterocyclic sulfonamides is described in Vascular Endothelial Growth Factor-dependent Human Umbilical Vascular Endothelial Cells (VEGF-HUVEC) and in HCT116 tumor cells in a soft agar diffusion assay.