New Amebacides. II. The Preparation of Some N-Alkyl-N-benzylhaloacetamides

AR Surrey, MK Rukwid

文献索引：Surrey; Rukwid Journal of the American Chemical Society, 1955 , vol. 77, p. 3798,3800

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被引用次数: 9

摘要

All of the 5-alkyl-N-benzyldichloroacetamides in Table I1 as well as the monochloroacetamides and trichloroacetamides listed in Table I11 were prepared by acylation of the appropriate N-alkylbenzylamine with monochloroacetyl, dichloroacetyl and trichloroacetyl chloride in the presence of dilute sodium hydroxide solution. For the most part the yields ranged from 45-80y0. About onehalf of the dichloroacetamides were obtained ...