Structure-activity relationships of a series of substituted benzamides: Potent D2/5-HT2 antagonists and 5-HT1a agonists as neuroleptic agents

MH Norman, GC Rigdon, WR Hall…

文献索引：Journal of Medicinal Chemistry, , vol. 39, # 5 p. 1172 - 1188

被引用次数: 39

摘要

... Journal of Medicinal Chemistry. ... Chemistry. Several synthetic routes were examined for assembling the desired substituted benzamides from their benzoyl chloride, benzoic acid, and isatoic anhydride precursors. The ...

652-39-1

3-氟邻苯二甲酸酐

174463-53-7

8-氟-2H-3,1-苯并噁嗪...

3-(1, 1-Dioxo-2 H-(1, 2, 4)-benzothiadiazin-3-yl)-4-hydroxy-...

[Tedesco, Rosanna; Shaw, Antony N.; Bambal, Ramesh; Chai, Deping; Concha, Nestor O.; Darcy, Michael G.; Dhanak, Dashyant; Fitch, Duke M.; Gates, Adam; Gerhardt, Warren G.; Halegoua, Dina L.; Han, Chao; Hofmann, Glenn A.; Johnston, Victor K.; Kaura, Arun C.; Liu, Nannan; Keenan, Richard M.; Lin-Goerke, Juili; Sarisky, Robert T.; Wiggall, Kenneth J.; Zimmerman, Michael N.; Duffy, Kevin J. Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 971 - 983]