Butenolide endothelin antagonists with improved aqueous solubility

WC Patt, XM Cheng, JT Repine, C Lee…

文献索引：Journal of Medicinal Chemistry, , vol. 42, # 12 p. 2162 - 2168

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被引用次数: 18

摘要

... Journal of Medicinal Chemistry. ... These peptides exert their actions via activation of two distinct receptor subtypes, ET A and ET B . Antagonists of these receptors have received numerous citations in the recent pharmaceutical literature. ...