Novel disulfides with antitumour efficacy and specificity
R Griffiths, WWL Wong, SP Fletcher, LZ Penn…
文献索引：Griffiths, Rebecca; Wong, W. Wei-Lynn; Fletcher, Stephen P.; Penn, Linda Z.; Langler, Richard F. Australian Journal of Chemistry, 2005 , vol. 58, # 2 p. 128 - 136
Abstract Some disulfides have previously been shown to possess antifungal and/or antileukaemic activity. Importantly, this cytotoxicity can be selective. We have previously shown that a subset of these compounds does not block the proliferative potential of normal, non-transformed cells. Based on these results and proposed mechanisms of action, a new set of structurally modified organosulfur compounds, including α-substituted disulfides and ...
