Bioorganic & Medicinal Chemistry Letters 2000-06-05

Methaqualone derivatives are potent noncompetitive AMPA receptor antagonists.

B L Chenard, F S Menniti, M J Pagnozzi, K D Shenk, F E Ewing, W M Welch

文献索引：Bioorg. Med. Chem. Lett. 10(11) , 1203-5, (2000)

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摘要

Quinazolin-4-one derivatives of methaqualone substituted at C-2 define a new class of noncompetitive antagonists at AMPA receptors.