Natural Product Research 2007-03-01

Callus of Securinega suffruticosa, a cell line accumulates dextro Securinega alkaloids.

Wei Yuan, Ping Zhu, Kedi Cheng, Chao Meng, Lin Ma, Feng Wu, Huixin Zhu

文献索引：Nat. Prod. Res. 21(3) , 234-42, (2007)

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摘要

Investigations on callus cultures of Securinega suffruticosa indicated that the cell line of S. suffruticosa callus was able to accumulate four known Securinega alkaloids with dextro rotation but not levo rotation as reported before: virosecurinine (1), viroallosecurinine (2), 14,15-dihydrovirosecurinine (3) and ent-phyllanthidine (4). Time course studies on the growth of callus cultures were carried out. The effects of different plant growth regulators, sucrose concentrations on callus growth and virosecurinine production were also reported.