Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4

T Kubota, BC Lewis, DJ Elliot, PI Mackenzie…

文献索引：Molecular Pharmacology, , vol. 72, # 4 p. 1054 - 1062

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被引用次数: 46

摘要

... Address correspondence to: Professor John Miners, Department of Clinical Pharmacology, Flinders Medical Centre ... The incubation mixture, in a total volume of 0.2 ml, contained UDPGA (5 ... and/or turnover, including the ability to bind multiple substrate molecules, occur between ...