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Synthesis and biological activity of metabolites of the antidiabetic, antihyperglycemic agent pioglitazone

SP Tanis, TT Parker, JR Colca, RM Fisher…

文献索引:Journal of Medicinal Chemistry, , vol. 39, # 26 p. 5053 - 5063

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被引用次数: 53

摘要

... Journal of Medicinal Chemistry. ... Chemistry. We elected to pursue the synthesis of metabolites 6−8 from a common pyridine precursor, methyl 6-methylnicotinate, to maximize the utility of common precursors. In order ...

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