Modular synthesis of heterocyclic carbene precursors

A Paczal, AC Bényei, A Kotschy

文献索引：Paczal, Attila; Benyei, Attila C.; Kotschy, Andras Journal of Organic Chemistry, 2006 , vol. 71, # 16 p. 5969 - 5979

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被引用次数: 72

摘要

A series of N-heterocyclic carbene precursors, containing an imidazoline or tetrahydropyrimidine framework, were prepared from ω-chloroalkanoyl chlorides. The sequential attachment of nitrogen nucleophiles and subsequent ring closure gave, depending on the reagents used, either the desired dihydroimidazolium and tetrahydropyrimidinium salts or their parent heterocycles. In this latter case, the second ...