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The role of Zn–OR and Zn–OH nucleophiles and the influence of para-substituents in the reactions of binuclear phosphatase mimetics

LJ Daumann, KE Dalle, G Schenk, RP McGeary…

文献索引:Daumann, Lena J.; Dalle, Kristian E.; Schenk, Gerhard; McGeary, Ross P.; Bernhardt, Paul V.; Ollis, David L.; Gahan, Lawrence R. Dalton Transactions, 2012 , vol. 41, # 6 p. 1695 - 1708

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被引用次数: 27

摘要

Analogues of the ligand 2, 2′-(2-hydroxy-5-methyl-1, 3-phenylene) bis (methylene) bis ((pyridin-2-ylmethyl) azanediyl) diethanol (CH3H3L1) are described. Complexation of these analogues, 2, 6-bis (((2-methoxyethyl)(pyridin-2-ylmethyl) amino) methyl)-4-methylphenol (CH3HL2), 4-bromo-2, 6-bis (((2-methoxyethyl)(pyridin-2-ylmethyl) amino) methyl) phenol (BrHL2), 2, 6-bis (((2-methoxyethyl)(pyridin-2-ylmethyl) amino) methyl)-4-nitrophenol ( ...