Tetrahedron

Mild and selective deprotection of carbamates with Bu 4 NF

U Jacquemard, V Bénéteau, M Lefoix, S Routier…

文献索引：Jacquemard, Ulrich; Beneteau, Valerie; Lefoix, Myriam; Routier, Sylvain; Merour, Jean-Yves; Coudert, Gerard Tetrahedron, 2004 , vol. 60, # 44 p. 10039 - 10047

全文：HTML全文

被引用次数: 88

摘要

A new mild method allowing the removal of carbamates using TBAF in THF is reported. Reactions were performed on indole, indoline, N-methyl aniline, aniline and tryptamine derivatives. The observed selectivity according to the carbamates or the substrates is discussed. A mechanism is postulated.