Journal of Hazardous Materials 2009-04-30

Determination of gallium in human urine by supercritical carbon dioxide extraction and graphite furnace atomic absorption spectrometry.

Chia-Chan Wu, Hui-Ming Liu

文献索引：J. Hazard. Mater. 163(2-3) , 1239-45, (2009)

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摘要

This study presents supercritical carbon dioxide (scCO(2)) extraction as an inherently safer and cleaner sample treatment method for identifying trace gallium in urine samples. Extraction is performed in the presence of a fluorinated beta-diketones chelating agent, 2,2-dimethyl-6,6,7,7,8,8,8-heptafluoro-3,5-octanedione (HFOD), by unmodified scCO(2). Quantitative extractions are conducted at 80 degrees C and 20.7 MPa with 15 min static plus 15 min dynamic extractions, and are followed by analysis via graphite furnace atomic absorption spectroscopy (GFAAS). The proposed procedure is successfully applied to determine the concentrations of gallium in real urine samples spiked with various levels of gallium with satisfactory recoveries of 90.8-100.3% (n=6) and relative standard deviations <10%. A standard reference material (SRM), Seronorm Trace Elements Urine, is used to validate the accuracy of the proposed method.