An Efficient Approach to the Synthesis of Nucleosides: Gold (I)??Catalyzed N??Glycosylation of Pyrimidines and Purines with Glycosyl ortho??Alkynyl Benzoates

Q Zhang, J Sun, Y Zhu, F Zhang…

文献索引：Zhang, Qingju; Sun, Jiansong; Zhu, Yugen; Zhang, Fuyi; Yu, Biao Angewandte Chemie - International Edition, 2011 , vol. 50, # 21 p. 4933 - 4936

全文：HTML全文

被引用次数: 53

摘要

The synthesis of nucleosides has continuously been a topical subject in efforts to develop new therapeutic agents (eg, antitumor and antiviral drugs),[1] to manipulate genetic processes (eg, antisense oligonucleotides and RNA interference),[2] and to expand the genetic code and understand the scope and limits of Watson–Crick base pairing.[3] However, the key technique for such syntheses, namely, the N-glycosidic coupling of ...