Papain??specific activating esters in aqueous dipeptide synthesis

…, M Mariman, HIV Amatdjais??Groenen…

文献索引：de Beer, Roseri J.A.C.; Zarzycka, Barbara; Mariman, Michiel; Amatdjais-Groenen, Helene I.V.; Mulders, Marc J.; Quaedflieg, Peter J.L.M.; van Delft, Floris L.; Nabuurs, Sander B.; Rutjes, Floris P.J.T. ChemBioChem, 2012 , vol. 13, # 9 p. 1319 - 1326

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被引用次数: 9

摘要

Abstract Enzymatic peptide synthesis has the potential to be a viable alternative for chemical peptide synthesis. Because of the increasing commercial interest in peptides, new and improved enzymatic synthesis methods are desirable. In recently developed enzymatic strategies such as substrate mimetic approaches and enzyme-specific activation, use of the guanidinophenyl ester (OGp) group has been shown to suffer from some drawbacks. OGp ...