4??Substituted Thioquinolines and Thiazoloquinolines: Potent, Selective, and Tween??80 in vitro Dependent Families of Antitubercular Agents with Moderate in vivo …
Abstract Two new families of closely related selective, non-cytotoxic, and potent antitubercular agents were discovered: thioquinolines and thiazoloquinolines. The compounds were found to possess potent antitubercular properties in vitro, an activity that is dependent on experimental conditions of MIC determination (resazurin test and the presence or absence of Tween-80). To clarify the therapeutic potential of these compound ...
