Abstract Secondary amines react with N-aromatic 2-chlorides in the presence of a catalytic amount of cobalt chloride. When DPPP was added as ligand, the yield was further improved. The N-aromatic-containing tertiary amines formed are interesting due to their potential biological activity. This work represents the first cobalt-catalyzed approach to C–N bond formation involving N-aromatic 2-chlorides and secondary amines having a certain ...
