The Synthesis of Potential Anticancer Agents. XXXVI. N-Nitrosoureas. 1 II. Haloalkyl Derivatives

TP Johnston, GS McCaleb, PS Opliger…

文献索引：Journal of medicinal chemistry, , vol. 9, # 6 p. 892 - 911

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被引用次数: 119

摘要

... 1 Page 6. ... an 8SY0 yield of l-cyclohexyl-3-(2-fluoroethyl)ureu (3c), which i5 consonant with the usual behavior of nitros~ureas.~~~' 9) JL Iloi ... Kitrosation of 3a in undiluted formic acid with an equal volume of aqueous nitrite solution (5- 6%) gave a mixture of isomers (about 657G ...