Selective partial reduction of quinolines: Hydrosilylation vs. transfer hydrogenation
AM Voutchkova, D Gnanamgari, CE Jakobsche…
文献索引：Voutchkova, Adelina M.; Gnanamgari, Dinakar; Jakobsche, Charles E.; Butler, Chase; Miller, Scott J.; Parr, Jonathan; Crabtree, Robert H. Journal of Organometallic Chemistry, 2008 , vol. 693, # 10 p. 1815 - 1821
Two mild and versatile catalytic routes give regioselective hydrogenation of the heterocyclic ring of quinoline derivatives avoiding the high pressures of hydrogen required in the conventional hydrogenation route. Hydrosilylation using H3SiPh and catalyzed by [Rh (nbd)(PPh3) 2] PF6 at room temperature gives dihydroquinoline, a product not obtainable via direct hydrogenation. Hydrosilylation of the CN bond of PhCHNPh is also observed ...
