Specificities of calreticulin transacetylase to acetoxy derivatives of 3-alkyl-4-methylcoumarins: effect on the activation of nitric oxide synthase

A Kathuria, A Gupta, N Priya, P Singh, HG Raj…

文献索引：Kathuria, Abha; Gupta, Anjali; Priya, Nivedita; Singh, Prabhjot; Raj, Hanumantharao G.; Prasad, Ashok K.; Parmar, Virinder S.; Sharma, Sunil K. Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 4 p. 1550 - 1556

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被引用次数: 20

摘要

Calreticulin Transacetylase (CRTAase) catalyzes the transfer of acetyl groups from polyphenolic acetates (PAs) to the receptor proteins and modulates their biological activities. CRTAase was conveniently assayed by the irreversible inhibition of cytosolic glutathione S- transferase (GST) by the model acetoxycoumarin, 7, 8-diacetoxy-4-methylcoumarin (DAMC). We have studied earlier, the influence of acetoxy groups on the benzenoid ring, the effect ...