Organic Letters 2006-06-22

Synthesis of nonactin and the proposed structure of trilactone.

Yikang Wu, Ya-Ping Sun

文献索引：Org. Lett. 8(13) , 2831-4, (2006)

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摘要

[reaction: see text] An efficient enantioselective route to nonactin using a novel beta-inversion of an Evans syn aldol to construct the THF ring is presented. Through total synthesis, the structure for trilactone proposed in the literature is shown likely to be incorrect.