Iodide-catalyzed reductions: development of a synthesis of phenylacetic acids

…, JT Colyer, OR Thiel, M Dilmeghani Seran…

文献索引：Milne, Jacqueline E.; Storz, Thomas; Colyer, John T.; Thiel, Oliver R.; Dilmeghani Seran, Mina; Larsen, Robert D.; Murry, Jerry A. Journal of Organic Chemistry, 2011 , vol. 76, # 22 p. 9519 - 9524

全文：HTML全文

被引用次数: 21

摘要

A new convenient and scalable synthesis of phenylacetic acids has been developed via the iodide catalyzed reduction of mandelic acids. The procedure relies on in situ generation of hydroiodic acid from catalytic sodium iodide, employing phosphorus acid as the stoichiometric reductant.