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Synthesis and serotonergic activity of 5-(oxadiazolyl) tryptamines: potent agonists for 5-HT1D receptors

LJ Street, R Baker, JL Castro…

文献索引:Journal of Medicinal Chemistry, , vol. 36, # 11 p. 1529 - 1538

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被引用次数: 84

摘要

... A large pocket is available in the binding domain of the S-HT~D receptor which will accommodate relatively bulky groups, positioned at C6 of the indole, without loss Journal of Medicinal Chemistry, 1993, Vol. 36, No. 11 1533 ... Chemical Methods: General Directions. ...