Abstract The title compounds and the corresponding l-gulo derivatives were synthesised in 6 steps from benzyl 2, 3: 5, 6-di-O-isopropylidene-α-d-mannofuranoside. The K i values, determined from inhibition studies with α-d-mannosidases from jack beans, almonds, and calf liver, and β-d-mannosidase from Aspergillus wentii, ranged from 70 to 400μM for the mannitol derivative and from 1.2 to 20μM for 5-amino-5-deoxy-d-mannopyranose, ie, ...
