Journal of pharmaceutical sciences

Synthesis of sydnones as potential therapeutic agents

LB Kier, D Dhawan

文献索引：Kier,L.B.; Dhawan,D. Journal of Pharmaceutical Sciences, 1962 , vol. 51, # 11 p. 1058 - 1061

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被引用次数: 32

摘要

Abstract A number of new 3-alkyl sydnones have been prepared as potential therapeutic agents. A preliminary pharmacological evaluation indicated that these compounds were central nervous system stimulants. The partition coefficients between chloroform and water were determined and a correlation was found between this and the millimole dosage per kilogram in the sydnones with nonfunctional side chains. Ultraviolet and infrared data are ...