Abstract Copper bromide was found to be an efficient catalyst for a domino reaction sequence leading to 3-pyrrolines. The Cu (I)-catalyzed Crabbé reaction of propargyl sulfonamide and selective cycloisomerization of the allene intermediate were carried out using microwave irradiation conditions affording a wide range of 2-substituted-and 2, 5- disubstituted-3-pyrrolines. Mechanistic studies of the reaction intermediates revealed two ...
