Bioorganic & Medicinal Chemistry Letters 2010-01-01

The synthesis of novel fluorescent purine analogues modified by azacrown ether at C6

Hai-Ming Guo, Jing Wu, Hong-Ying Niu, Dong-Chao Wang, Feng Zhang, Gui-Rong Qu, Hai-Ming Guo, Jing Wu, Hong-Ying Niu, Dong-Chao Wang, Feng Zhang, Gui-Rong Qu

文献索引：Bioorg. Med. Chem. Lett. 20(10) , 3098-102, (2010)

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摘要

The synthesis and fluorescence properties of novel purine analogues linked azacrown ether at C6 position were investigated. These new purine analogues could be prepared from a series of 6-chloropurines and showed selective and efficient signaling behaviors toward micromolar concentration of Ag + ion over other common metal ions in an aqueous environment.