TMDS as a Dual??Purpose Reductant in the Regioselective Ring Cleavage of Hexopyranosyl Acetals to Ethers

…, W Dayoub, GR Chen, M Lemaire

文献索引：Zhang, Yin-Jie; Dayoub, Wissam; Chen, Guo-Rong; Lemaire, Marc Green Chemistry, 2011 , vol. 13, # 10 p. 2737 - 2742

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被引用次数: 3

摘要

Abstract 1, 1, 3, 3-Tetramethyldisiloxane (TMDS) has been developed as an excellent dual- purpose reductant for the highly regioselective ring cleavage of various hexopyranosyl 4, 6- O-acetals with Cu (OTf) 2 or AlCl 3 to afford the corresponding primary and secondary ethers. Its application to the concise synthesis of carbohydrate-based surfactants is highlighted.