Discovery of a novel series of biphenyl benzoic acid derivatives as potent and selective human β3-adrenergic receptor agonists with good oral bioavailability. Part I

M Imanishi, Y Tomishima, S Itou…

文献索引：Journal of Medicinal Chemistry, , vol. 51, # 6 p. 1925 - 1944

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被引用次数: 33

摘要

... Journal of Medicinal Chemistry. ... for a once daily oral administration (due to compliance issues), an agent that possesses the pharmacokinetic properties required for once daily oral administration is required to meet these growing (due to an aging population) medical needs. ...