Tetrahedron

Short and efficient preparations of isoxazole-3-carboxylic acid and imino-oxopentanoic acid potent precursors of 4-hydroxyisoleucine

…, SDL Marin, M Maruani, A Wagner, C Mioskowski

文献索引：Becht, Jean-Michel; Marin, Sandra De Lamo; Maruani, Martine; Wagner, Alain; Mioskowski, Charles Tetrahedron, 2006 , vol. 62, # 18 p. 4430 - 4434

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被引用次数: 10

摘要

Herein, we describe short and efficient syntheses of isoxazole-3-carboxylic acid and imino- oxopentanoic acid achiral precursors of 4-hydroxyisoleucine. The developed procedures involve readily available and cheap starting materials and can easily be transposed to the large scale.

~88%

Potent and selective inhibitors of long chain l-2-Hydroxy ac...

[Barawkar, Dinesh A.; Meru, Ashwin; Bandyopadhyay, Anish; Banerjee, Abir; Deshpande, Anil M.; Athare, Chandrashekhar; Koduru, Chandrasekhar; Khose, Goraksha; Gundu, Jayasagar; Mahajan, Koshu; Patil, Pradeep; Kandalkar, Sachin R.; Niranjan, Sanjay; Bhosale, Shubhangi; De, Siddhartha; Mukhopadhyay, Sudit; Chaudhary, Sumit; Koul, Summon; Singh, Umesh; Chugh, Anita; Palle, Venkata P.; Mookhtiar, Kasim A.; Vacca, Joseph; Chakravarty, Prasun K.; Nargund, Ravi P.; Wright, Samuel D.; Roy, Sophie; Graziano, Michael P.; Singh, Sheo B.; Cully, Doris; Cai, Tian-Quan ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 12 p. 919 - 923]