Rhodium (I)-catalyzed direct carboxylation of arenes with CO2 via chelation-assisted C− H bond activation

H Mizuno, J Takaya, N Iwasawa

文献索引：Mizuno, Hajime; Takaya, Jun; Iwasawa, Nobuharu Journal of the American Chemical Society, 2011 , vol. 133, # 5 p. 1251 - 1253

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被引用次数: 156

摘要

Rh-catalyzed direct carboxylation of unactivated aryl C− H bond under atmospheric pressure of carbon dioxide was realized via chelation-assisted C− H activation for the first time. Variously substituted and functionalized 2-arylpyridines and 1-arylpyrazoles underwent the carboxylation in the presence of the rhodium catalyst and a stoichiometric methylating reagent, AlMe2 (OMe), to give carboxylated products in good yields. The ...