Synthesis

Indium (III) chloride/2-iodoxybenzoic acid: A novel reagent system for the conversion of indoles into isatins

JS Yadav, BVS Reddy, CS Reddy, AD Krishna

文献索引：Yadav; Subba Reddy; Reddy, Ch. Suresh; Krishna Synthesis, 2007 , # 5 p. 693 - 696

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被引用次数: 23

摘要

Abstract Indoles and azaindoles undergo smooth oxidation with 2-iodoxybenzoic acid (IBX) in the presence of indium (III) chloride at 80 C to afford the corresponding isatins in excellent yields. This method is very useful for the direct preparation of isatins from indoles. The reaction proceeds smoothly in aqueous media and the products are obtained in excellent yields.