Journal of the American Chemical Society

Pyrimidine Nuclear Organometallic Compounds. The Synthesis of 6-Acyluracils and Orotic Acid-C14O2H

BW Langley

文献索引：Langley Journal of the American Chemical Society, 1956 , vol. 78, p. 2136,2140

全文：HTML全文

被引用次数: 36

摘要

The preparation of 2, 4-diethoxy-6-pyrimidylmagnesium bromide and 2,~-dietlioxy-G- pyrinlid~ llitl1iurn is described. 2, 4-Diethoxy-6-pyrimidylcarbinols obtained from the latter have been converted by successive oxidation and hydrolysis into 6-acyluracils. Carbonation of the lithium compound with C1* O~ and hydrolysis of the product gave orotic acid-C1lOzH.