Organic letters

Practical Approach for Preparation of Unsymmetric Benzils from β-Ketoaldehydes

L Ruan, M Shi, N Li, X Ding, F Yang, J Tang

文献索引：Ruan, Libo; Shi, Min; Li, Nian; Ding, Xu; Yang, Fan; Tang, Jie Organic Letters, 2014 , vol. 16, # 3 p. 733 - 735

全文：HTML全文

被引用次数: 12

摘要

An efficient and practical method for the synthesis of unsymmetric benzils from readily available β-ketoaldehydes has been developed. Various unsymmetric 1, 2-diaryldiketones bearing functional groups have been obtained in good to excellent yields under mild reaction conditions. A plausible mechanism was proposed, and α, α-dichloroketone was considered as the key intermediate. The generation of α, α-dichloroketones from β- ...