Some regioselective cross-coupling reactions of halopyridines and halopyrimidines

NM Simkovsky, M Ermann, SM Roberts…

文献索引：Simkovsky, Nadja M.; Ermann, Monika; Roberts, Stanley M.; Parry, David M.; Baxter, Andy D. Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 16 p. 1847 - 1849

全文：HTML全文

被引用次数: 27

摘要

An efficient procedure for cross-coupling of 3-bromopyridine and 4-bromoanisole to various mono- and dichloro heteroaryl compounds—giving the corresponding biaryls in 74–96% yield—is described. ... Herein we report a high yielding protocol for the preparation of bipyridines, pyridylpyrimidines, and pyridylquinolines with excellent regio-control employing palladium-catalysed cross-coupling reactions. ... As an approach to heteroaryl pyridines ...