Acta Crystallographica Section E 2007-01-01

Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxy-pyrimidine-anthranilic acid (1/1).

Kaliyaperumal Thanigaimani, Packianathan Thomas Muthiah, Daniel E Lynch

文献索引：Acta Crystallogr. Sect. E Struct. Rep. Online 64(Pt 1) , o107-8, (2007)

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摘要

In the title cocrystal, C(6)H(9)N(3)O(2)·C(7)H(7)NO(2), the asymmetric unit contains two crystallographically independent 2-amino-4,6-dimeth-oxy pyrimidine-anthranilic acid adducts. The 2-amino-4,6-dimeth-oxy pyrimidine mol-ecules inter-act with the carboxylic group of the respective anthranilic acid mol-ecules through N-H⋯O and O-H⋯N hydrogen bonds, forming a cyclic hydrogen-bonded motif R(2) (2)(8). The pyrimidine mol-ecules also form base pairs via a pair of N-H⋯N hydrogen bonds, forming another R(2) (2)(8) motif. The typical intra-molecular N-H⋯O hydrogen bond is observed in the anthranilic acid mol-ecules. Furthermore, the crystal structure is stabilized by C-H⋯O hydrogen bonds.