Mucochloric Acid: A Useful Synthon for the Selective Synthesis of 4??Aryl??3??chloro??2 (5H)??furanones,(Z)??4??Aryl??5??[1??(aryl) methylidene]??3??chloro??2 (5H)??furanones …

F Bellina, C Anselmi, F Martina…

文献索引：Bellina, Fabio; Anselmi, Chiara; Martina, Francesca; Rossi, Renzo European Journal of Organic Chemistry, 2003 , # 12 p. 2290 - 2302

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被引用次数: 39

摘要

Abstract 3, 4-Dichloro-2 (5H)-furanone, which has been prepared efficiently from mucochloric acid, has been transformed selectively into 4-aryl-3-chloro-2 (5H)-furanones either by Suzuki-or Stille-type reactions. These monochloro derivatives have been used as precursors either to (Z)-4-aryl-5-[1-(aryl) methylidene]-3-chloro-2 (5H)-furanones, including naturally occurring rubrolide M, or to unsymmetrical 3, 4-diaryl-2 (5H)-furanones. Some 2 ( ...