Journal of the American Chemical Society 2004-06-02

Facile formation of an intrastrand cross-link lesion between cytosine and guanine upon pyrex-filtered UV light irradiation of d((Br)CG) and duplex DNA containing 5-bromocytosine.

Yu Zeng, Yinsheng Wang

文献索引：J. Am. Chem. Soc. 126(21) , 6552-3, (2004)

全文：HTML全文

摘要

Pyrex-filtered UV light irradiation of d(BrCG) and 5-bromocytosine-containing duplex DNA leads to facile formation of a cross-link lesion between the C5 carbon atom of cytosine and the C8 carbon atom of its adjacent guanine. A similar cross-link lesion has been previously found in the X-ray irradiation mixture of d(CGTA).