Epilepsy & Behavior 2011-05-01

Efficacy of hippocampal transection for left temporal lobe epilepsy without hippocampal atrophy.

Shigeki Sunaga, Michiharu Morino, Taro Kusakabe, Hidenori Sugano, Hiroyuki Shimizu, Shigeki Sunaga, Michiharu Morino, Taro Kusakabe, Hidenori Sugano, Hiroyuki Shimizu

文献索引：Epilepsy Behav. 21(1) , 94-9, (2011)

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摘要

We describe a case of left temporal lobe epilepsy without hippocampal atrophy. A 31-year-old woman presented with typical symptoms of complex partial seizures. Magnetic resonance imaging demonstrated slightly obscure internal structures in the left hippocampus. Scalp electroencephalography revealed interictal epileptiform discharges in the left temporal lobe. A Wada test with propofol determined the language-dominant hemisphere to be the left. Intraoperative electrocorticography revealed active epileptic discharges in the hippocampus and the anterior temporal basal area. The hippocampal epileptic area was treated with multiple transection, which led to the complete cessation of epileptic discharges. After surgery, the Rey Auditory Verbal Learning Test score decreased from 12 to 9. However, it returned to the preoperative level 6months after surgery. We describe this case as a typical example demonstrating the efficacy of hippocampal transection for seizure control and the preservation of verbal memory.Copyright © 2011 Elsevier Inc. All rights reserved.