Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists

R Jiang, X Song, P Bali, A Smith, CR Bayona…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 12 p. 3890 - 3894

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被引用次数: 7

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Through traditional medicinal chemistry structure–activity relationships (SAR), installation of various groups at the 3–6-positions of the ... we introduced substituents at positions 3–6 of the piperidine ring using the chemistry highlighted in ...