Tetrahedron Letters

Metal-free C–N bond-forming reaction: straightforward synthesis of anilines, through cleavage of aryl C–O bond and amide C–N bond

J Yu, P Zhang, J Wu, Z Shang

文献索引：Yu, Jianzhong; Zhang, Peizhi; Wu, Jun; Shang, Zhicai Tetrahedron Letters, 2013 , vol. 54, # 24 p. 3167 - 3170

被引用次数: 5

摘要

An efficient metal-free C–N bond forming reaction through cleavage of aryl C–O bond and amide C–N bond has been developed. This process represents a practical method for the facile construction of anilines with a broad substrate scope and wide functional group tolerance in moderate to excellent yields.

~35%

~76%

~53%

~58%

~57%

~38%

~43%

~50%

~63%

~81%

~79%

~37%

~65%

~51%

~46%

~32%

~5%

~54%

~87%

~85%

~57%

~49%

~49%

~66%

~74%

~95%

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