Transition-metal-catalyzed asymmetric allylic substitution reactions constitute one of the most convenient approaches for the generation of optically active allylic amines.[1] The best solutions for the enantioselective synthesis of optically active amines from precursor allylic alcohols to date involve the use of primary allylic esters,[2a, b] carbonates,[2c–l] and phosphates [2m] as substrates. Substitution of a racemic mixture of secondary allylic ...
