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One-pot synthesis of salicylanilides by direct amide bond formation from salicyclic acid under microwave irradiation

…, B Zhao, YP Jiang, H Ding, S Yang

文献索引:Lu, Cheng-Rong; Zhao, Bei; Jiang, Ying-Peng; Ding, Hao; Yang, Sheng Synthetic Communications, 2011 , vol. 41, # 9 p. 1257 - 1266

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被引用次数: 3

摘要

Abstract A highly efficient protocol for the preparation of aromatic amides is described by the direct reactions between salicyclic acid and aromatic amines in the presence of phosphorous trichloride under microwave irradiation. The method has several advantages over the conventional methods, including operational simplicity, good yield, and reduced reaction time.