Tetrahedron

Synthesis and luminescence properties of biphenyl-type firefly luciferin analogs with a new, near-infrared light-emitting bioluminophore

C Miura, M Kiyama, S Iwano, K Ito, R Obata, T Hirano…

文献索引：Miura, Chihiro; Kiyama, Masahiro; Iwano, Satoshi; Ito, Kazuto; Obata, Rika; Hirano, Takashi; Maki, Shojiro; Niwa, Haruki Tetrahedron, 2013 , vol. 69, # 46 p. 9726 - 9734

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被引用次数: 8

摘要

Abstract New firefly luciferin analogs of the 4, 4′-substituted biphenyl-type were synthesized. One analog with a 4′-dimethylamino group possessed bioluminescence activity, emitting near-infrared biological window light at 675 nm suitable for deep-site bioimaging of living animals. The chemiluminescence light-emission maximum of the corresponding methyl ester of the bioluminescence active analog was 500 nm, implying ...